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Daniel C Danila Selected Research

monomethyl auristatin E

10/2019A phase I study of the antibody drug conjugate ASG-5ME, an SLC44A4-targeting antibody carrying auristatin E, in metastatic castration-resistant prostate cancer.

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Daniel C Danila Research Topics

Disease

40Prostatic Neoplasms (Prostate Cancer)
01/2022 - 04/2007
21Neoplasms (Cancer)
01/2022 - 11/2003
17Circulating Neoplastic Cells
01/2021 - 04/2007
6Neoplasm Metastasis (Metastasis)
01/2022 - 12/2007
3Fatigue
11/2020 - 04/2010
3Disease Progression
01/2019 - 01/2013
3Pituitary Neoplasms (Pituitary Adenoma)
11/2003 - 03/2002
2Bone Diseases (Bone Disease)
01/2017 - 04/2010
1Sepsis (Septicemia)
01/2022
1Chromosomal Instability (Chromosome Stability)
01/2021
1Nausea
11/2020
1Breast Neoplasms (Breast Cancer)
11/2020
1Stomatitis
01/2020
1Pneumonia (Pneumonitis)
01/2020
1Hyponatremia
10/2019
1Neutropenia
10/2019
1Exanthema (Rash)
10/2019
1Diarrhea
10/2019
1Constipation
10/2019
1Hypoxia (Hypoxemia)
10/2019
1Abdominal Pain (Pain, Abdominal)
10/2019
1Microsatellite Instability
04/2019
1Hypocalcemia
08/2015
1Carcinoma (Carcinomatosis)
12/2012
1Hypokalemia
03/2010
1Hypertension (High Blood Pressure)
03/2010
1Hyperaldosteronism (Conn Syndrome)
03/2010

Drug/Important Bio-Agent (IBA)

11Androgen Receptors (Androgen Receptor)IBA
01/2022 - 04/2007
11Biomarkers (Surrogate Marker)IBA
07/2020 - 06/2011
9Prostate-Specific Antigen (Semenogelase)IBA
01/2022 - 12/2007
7AndrogensIBA
01/2022 - 03/2009
6Abiraterone AcetateIBA
12/2021 - 03/2010
5Messenger RNA (mRNA)IBA
01/2019 - 03/2002
4Proteins (Proteins, Gene)FDA Link
01/2022 - 04/2007
4enzalutamideIBA
01/2021 - 04/2010
4Immunoconjugates (Immunoconjugate)IBA
08/2020 - 10/2019
4Pharmaceutical PreparationsIBA
01/2017 - 06/2011
3taxaneIBA
01/2022 - 01/2017
3AntigensIBA
12/2019 - 01/2019
3Indicators and Reagents (Reagents)IBA
11/2019 - 06/2013
2Prednisone (Sone)FDA LinkGeneric
12/2021 - 03/2010
2abirateroneIBA
01/2021 - 01/2020
2Lipase (Acid Lipase)FDA Link
11/2020 - 01/2020
2Dihydrotestosterone (Androstanolone)IBA
01/2020 - 10/2013
2apalutamideIBA
01/2017 - 10/2013
2RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA
12/2012 - 11/2012
2DNA (Deoxyribonucleic Acid)IBA
12/2012 - 04/2007
2Docetaxel (Taxotere)FDA Link
03/2010 - 03/2010
2Complementary DNA (cDNA)IBA
11/2003 - 03/2002
2Protein Isoforms (Isoforms)IBA
11/2003 - 10/2002
1niraparibIBA
01/2022
1Poly(ADP-ribose) Polymerase InhibitorsIBA
01/2022
1Testosterone (Sustanon)FDA Link
12/2021
1acetyl- 2- naphthylalanyl- 3- chlorophenylalanyl- 1- oxohexadecyl- seryl- 4- aminophenylalanyl(hydroorotyl)- 4- aminophenylalanyl(carbamoyl)- leucyl- ILys- prolyl- alaninamideFDA Link
12/2021
1antiarrhythmic peptide (AAP)IBA
12/2021
1LY3022855IBA
11/2020
1Dasatinib (BMS 354825)FDA Link
11/2020
1Creatine Kinase (Creatine Phosphokinase)IBA
11/2020
1Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
11/2020
1Phosphotransferases (Kinase)IBA
11/2020
1temsirolimusFDA Link
01/2020
1cixutumumabIBA
01/2020
1TensinsIBA
01/2020
1Deoxyglucose (2 Deoxy D glucose)IBA
01/2020
1PlatinumIBA
01/2020
1PTEN Phosphohydrolase (PTEN Phosphatase)IBA
01/2020
1TOR Serine-Threonine KinasesIBA
01/2020
1TroponinIBA
10/2019
1ASG-5MEIBA
10/2019
1auristatinIBA
10/2019
1monomethyl auristatin EIBA
10/2019
1Programmed Cell Death 1 ReceptorIBA
04/2019
1B7-H1 AntigenIBA
04/2019
1Immune Checkpoint InhibitorsIBA
04/2019
1pembrolizumabIBA
04/2019
1MLN 8237IBA
01/2019
1Aurora Kinase AIBA
01/2019
1Hormones (Hormone)IBA
01/2019
1AntibodiesIBA
01/2019
1Alkaline PhosphataseIBA
01/2017
1DenosumabFDA Link
08/2015
1Kazal Pancreatic Trypsin InhibitorIBA
09/2014
1Androgen Antagonists (Antiandrogens)IBA
10/2013
1Itraconazole (Sporanox)FDA LinkGeneric
01/2013
1EnzymesIBA
12/2012
1RNA (Ribonucleic Acid)IBA
11/2012
1Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
11/2011
1Biological ProductsIBA
11/2011
1Serine Proteases (Serine Protease)IBA
11/2011
1Steroid 17-alpha-Hydroxylase (17 alpha Hydroxylase)IBA
03/2010
1MineralocorticoidsIBA
03/2010
1LigandsIBA
03/2010

Therapy/Procedure

36Castration
01/2022 - 04/2007
16Therapeutics
01/2022 - 04/2007
5Drug Therapy (Chemotherapy)
01/2020 - 12/2007
2Prostatectomy (Retropubic Prostatectomy)
12/2021 - 01/2017
1Radiotherapy
12/2021
1Lymph Node Excision (Lymph Node Dissection)
01/2017
1Combined Modality Therapy
01/2017
1Drug Tapering
04/2010